杨静，女，博士，特聘副研究员，硕士研究生导师。2017年毕业于苏州大学药学院，获得医学博士学位。2014-2017为苏州大学-哈佛大学麻省总医院联合培养博士，2017-2019哈佛大学麻省总医院博士后。2020年10月加入中国药科大学工学院生物医学工程教研室。目前主持有江苏省自然科学基金1项，国家自然科学基金青年科学基金项目1项，中国药科大学高层次人才引进项目1项（100万）。近年来在Nature Communications, Chemical Science, Chemical Communications等国际权威期刊发表论文20余篇。

联系方式：yangjing@cpu.edu.cn

研究方向：

1. 小分子光学探针的构建及在AD诊疗中的应用

2. 抗肿瘤蛋白降解药物分子的设计及活性研究

3. 棕色脂肪的成像研究

代表性论文：

Jing Yang^#, Wei Yin^#, Richard Van, Keyi Yin, Peng Wang, Chao Zheng, Biyue Zhu, Kathleen Ran, Can Zhang, Mohanraja Kumar, Yishan Shao, Chongzhao Ran. Turn-on chemiluminescence probes and dual-amplification of signal for detection of amyloid beta species in vivo. Nature Communications, 2020, 11(1), 1-14.

Jing Yang^#, Biyue Zhu^#, Wei Yin, Zhihao Han, Chao Zheng, Peng Wang, Chongzhao Ran. Differentiating Ab40 and Ab42 in amyloid plaques with a small molecule fluorescence probe.Chemical Science, 2020, 11 (20), 5238-5245.

Jing Yang^#, Jian Yang^#, Huan Wang, Junfeng Wang, Jianping Xiong, Chunhua Qiao, Chongzhao Ran.. Atom-economical design of PET tracer for imaging α_vβ₃ integrin via utilizing three-in-one function of ⁶⁴Copper. Chemical Communications, 2020, 56 (12), 1788-1791.  

Jian Yang^#, Jing Yang^#, Yuyan Li, Yungen Xu,  Ran, C. Z. Near-infrared Fluorescence Ocular Imaging (NIRFOI) of Alzheimer’s Disease. Molecular Imaging and Biology, 2019, 21 (1), 35-43.

Liguo Wang, Jing Yang*, Huan Wang, Chongzhao Ran, Ying Su, Long Zhao*. A highly selective turn-on fluorescent probe for the detection of aluminum and its application to bio-imaging.Sensors,2019, 19 (11), 1-10.

Jing Yang, Jian Yang, Chongzhao Ran. Spectral Unmixing Imaging for Differentiating Brown Adipose Tissue Mass and Its Activation.Contrast Media & Molecular Imaging, 2018, 2018, 1-7.

Jing Yang^#, Xueli Zhang^#, Yiying Zhu, Emily Lenczowski, Yanli Tian, Jian Yang, Can Zhang, Markus Hardt, Chunhua Qiao, Rudolph E. Tanzi, Anna Moore, Hui Ye, Chongzhao Ran. A double-edged role of copper in the fate of amyloid beta in the presence of anti-oxidants. Chemical Science, 2017, 8 (9), 6155-6164.

Jing Yang, Zhengtao Tu, Xin Xu, Jinfeng Luo, Xing Yan, Chongzhao Ran, Xinliang Mao, Ke Ding, Chunhua Qiao. Novel Conjugates of Endoperoxide and 4-Anilinoquinazoline as Potent Anticancer Agents.Bioorganic & Medicinal Chemistry Letters, 2017, 27 (6), 1341-1345.

Jing Yang^#, Jian Yang^#, Lu Wang, Anna Moore, Steven. H Liang, Chongzhao Ran. Yang, J., Yang, J., Wang, L., Moore, A., Liang, S. H., Ran, C. Z. Synthesis-free PET imaging of brown adipose tissue and TSPO via combination of disulfiram and ⁶⁴CuCl₂. Scientific Reports, 2017, 7, 1-9.

Jing Yang, Yanli Liu, Chengwen Xue, Wei Yu, Jian Zhang, Chunhua Qiao. Synthesis and biological evaluation of glaucocalyxin A derivatives as potential anticancer agents. European Journal of Medicinal Chemistry, 2014, 86, 235-241.

Huanqiu Li^#, Jing Yang^#, Shuhua Ma, Chunhua, Qiao. Structure-based design of rhodanine-based acylsulfonamide derivatives as antagonists of the anti-apoptotic Bcl-2 protein. Bioorganic & Medicinal Chemistry, 2012, 20 (14), 4194-4200.